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Notice for objection to sale of shares held by untraceable shareholders

Company Name:°®¶¹´«Ã½.
Director, President and CEO:Haruo Naito

Securities Code:4523
Listed Locations:First Sections of the Tokyo
Stock Exchange and the Osaka
Securities Exchange
Inquiries:Yuji Matsue Vice President, Manager of Corporate
Communications Phone 03-3817-5120

Notice for objection to sale of shares held by untraceable shareholders

°®¶¹´«Ã½. (Headquarters: Tokyo; Director, President & CEO: Haruo Naito) is searching for untraceable shareholders: those with whom we have been unable to contact for 5 years and have not collected dividends for the same period of time.

Matters concerning untraceable shareholders shall be handled in accordance with Article 198 of the Company Act Between November 1, 2010 and February 7, 2011, the notice set out below shall be published.

In the notice, untraceable shareholders and other concerned parties are asked to contact Mitsubishi UFJ Trust and Banking Corporation, manager of Eisai’s shareholder register by February 7, 2011.

In the interests of improving share management services, all shares held by shareholders who fail to come forward by February 7, 2011, the end of the advertisement period, will be scheduled for sale in accordance with Article 197 of the Company Act. Revenue from sold shares shall be held for 10 years, during which time revenues will be paid upon the request of shareholders coming forward.

1.Outline of Untraceable Shareholder Share Sales System

Untraceable shareholders are those shareholders with whom correspondence to the address on the shareholder register has not been able to be delivered for 5 years or more, and no dividend has been collected for 5 years.

The term Untraceable Shareholder Share Sales System refers to the auction or sale of shares held by untraceable shareholders, by way of advertisement and notice as stipulated in the Company Act. The system allows for revenue from the sale of shares to be returned to the original shareholder.

2.Content of the Notice and Publication Means

The notice, to be published from November 1, 2010, shall list share numbers, the names and addresses of shareholders and numbers of shares held according to the share register. The means of publication shall be by electronic public notice as stipulated in the Articles of Incorporation. This notification shall be published at the following URL:

3.Schedule

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November 1, 2010 Notice for objection to sale of shares of untraceable shareholders
February 7, 2011 Deadline for objection to sale of shares of untraceable shareholders
February 8, 2011 and on Sale of shares held by untraceable shareholders

4.Contact Details

Share Register Manager Mitsubishi UFJ Trust and Banking Corporation
Securities Trading Department
7-10-11 Higashisuna, Koto-ku
Tokyo 137-8081
Phone 0120-232-711 (toll free)